早期动态18F-FDG PET/CT成像在实体肿瘤评估中的应用

~(18)F-FDG PET/CT常规代谢成像反应肿瘤的葡萄糖代谢及乏氧情况,而~(18)F-FDG PET/CT早期动态成像能反映PET/CT成像早期肿瘤的灌注情况。由于肿瘤的异质性,在早期动态~(18)F-FDG PET/CT成像,即~(18)F-FDG PET/CT灌注成像中,存在独立于常规60 min~(18)F-FDG PET/CT代谢成像的SUVmax(最大标准摄取值)高摄取区。因此,在临床工作中应用~(18)F-FDG PET/CT早期动态成像,能够进一步对实体肿瘤的活性区域进行评估,能够更好评价患者预后、完善治疗方案。当前~(18)F-FDG早期动态成像已经应用在肝癌、肾癌以及膀胱癌等实体肿瘤诊断中。早期动态~(18)F-FDG PET/CT成像结合常规标准~(18)F-FDG PET/CT代谢成像,对实体肿块进行一站式成像方法,能够更好的对肿瘤进行评估。

Application of Early Dynamic 18F-FDG PET/CT Imaging in Solid Tumor Assessment

ABSTRACT: ¹⁸F-FDG PET/CT Whole Body imaging reflects tumor glucose metabolism and hypoxia, while ¹⁸F-FDG PET/CT early dynamic imaging can reflect PET/CT imaging of early tumors. Perfusion situation. Due to tumor heterogeneity, in early dynamic ¹⁸F-FDG PET/CT imaging, ¹⁸F-FDG PET/CT perfusion imaging, there is a SUVmax (maximum standard uptake value) independent of conventional 60 min ¹⁸F-FDG PET/CT metabolic imaging. High intake area. Therefore, the application of ¹⁸F-FDG PET/CT early dynamic imaging in clinical work can further evaluate the active area of solid tumors, which can better evaluate the prognosis of patients and improve the treatment plan. The current ¹⁸F-FDG early dynamic imaging has been applied to the diagnosis of solid tumors such as liver cancer, kidney cancer and bladder cancer. Early dynamic ¹⁸F-FDG PET/CT imaging combined with conventional standard ¹⁸F-FDG PET/CT metabolic imaging, a one-stop imaging method for solid tumors, can better evaluate the tumor.