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Histochemistry of the juxtaglomerular apparatus in the toad Bufo bufo
Authors:Dr. A. P. M. Lamers  G. J. A. Speijers  A. M. Stadhouders
Affiliation:(1) Biological Laboratory Medical Faculty, University of Nijmegen, The Netherlands;(2) Laboratory for Submicroscopic Morphology, Medical Faculty, University of Nijmegen, The Netherlands;(3) Biological Laboratory, Medical Faculty, Geert Grooteplein Noord 21, Nijmegen, The Netherlands
Abstract:Summary An investigation regarding the question of whether there exists a macula densa as part of the juxtaglomerular apparatus in the kidney of amphibians has been carried out. With the aid of a histochemical reaction for glucose-6-phosphate dehydrogenase activity, the presence of a macula densa zone as a specialized part of the distal tubule in the toad Bufo bufo was demonstrated. The functional significance of the high glucose-6-phosphate dehydrogenase activity in the macula densa cells is discussed.
Keywords:Kidney  Bufo bufo  Juxtaglomerular apparatus  Macula densa  Glucose-6-phosphate dehydrogenase
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