Microrheological characteristics of reticulocyte in vivo |
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| Authors: | Lide Xie Dagong Sun Weijuan Yao Zongyao Wen |
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| Affiliation: | Hemorheology Center, Department of Biophysics, School of Basic Medical Sciences, Peking University, Beijing 100083, China |
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| Abstract: | Using the method of phenylhydrazine-induced anemia in rabbits, a mass of new reticulocytes, which synchronously grow, were got in vivo. The measurements of deformation index, orientation index, electrophoresis mobility etc. were performed for more than 72 h in the process of reticulocytes turning into red blood cells in vivo. There were obvious changes in the micro- rheological characteristics of reticulocytes in the course of turning into erythrocytes. The present study is significant in clinic for studying erythrocytes' microrheological characteristics when there are a lot of reticulocytes in blood, and also important in basic theorem for studying reticulocytes microrheological characteristics. It makes up a deficiency in the study on microrheological characteristics of reticulocytes turning into new RBCs from reticulocytes during reticulocytes life span. |
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| Keywords: | phenylhydrazine reticulocyte microrheological characteristics deformation indexes orientation indexes new ektacytometry |
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