Glycerol 3-phosphate inhibits swarming and aggregation of Myxococcus xanthus |
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Authors: | Moraleda-Muñoz A Carrero-Lérida J Extremera A L Arias J M Muñoz-Dorado J |
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Institution: | Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Granada, Spain. |
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Abstract: | We have cloned a gene of Myxococcus xanthus with similarities to the permease for glycerol 3-phosphate (G3P) of other bacteria. Expression of the gene increased significantly during the first hours of starvation. Swarming of the wild-type strain was inhibited and aggregation was delayed by G3P. Conversely, a DeltaglpT strain aggregated even on rich medium. These results indicate that G3P may function to regulate the timing of aggregation in M. xanthus. |
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