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Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen |
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| Authors: | Nishant K Singh Esam T Abualrous Cory M Ayres Frank Noé Ragul Gowthaman Brian G Pierce Brian M Baker |
| Institution: | 1. Computational Molecular Biology Group, Institute for Mathematics, Freie Universität Berlin, Berlin, Germany;2. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana
Harper Cancer Research Institute, University of Notre Dame, South Bend, Indiana;3. Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, Maryland;4. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana |
| Abstract: | |
| Keywords: | antigen binding geometry MHC peptide spherical coordinates structure T cell receptor |