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3,3-Bisaryloxindoles as mineralocorticoid receptor antagonists |
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| Authors: | Neel David A Brown Matthew L Lander Peter A Grese Timothy A Defauw Jean M Doti Robert A Fields Todd Kelley Sally Ann Smith Stephon Zimmerman Karen M Steinberg Mitchell I Jadhav Prabhakar K |
| Affiliation: | Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA. neel_david_a@lilly.com |
| Abstract: |  Syntheses and SAR studies of 3,3-bisaryloxindole analogues provided potent mineralocorticoid receptor (MR) antagonists that were selective over other steroid nuclear hormone receptors. |
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