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Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle Analysis
Affiliation:1. School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, China;2. Department of Biology, Southern University of Science and Technology, Shenzhen 518055, China;3. State Key Laboratory for Artificial Microstructures and Mesoscopic Physics, School of Physics, Peking University, Beijing 100871, China;4. Institute of Systems Biology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen 518055, China;5. Electron Microscopy Laboratory, School of Physics, Peking University, Beijing 100871, China;6. Computing Center of Peking University, Peking University, Beijing 100871, China;7. Peking-Tsinghua Center for Life Sciences, School of Physics, Peking University, Beijing 100871, China;8. Center for Quantitative Biology, Peking University, Beijing 100871, China;9. Joint Laboratory for Infectious Disease Prevention and Control, Hygienic Section of Longhua Center for Disease Control and Prevention, Shenzhen 518109, China
Abstract:
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  • Keywords:cryo-EM  IGF-1r  insulin  IGF-1
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