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Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State
Institution:1. Department of Biochemistry, Ludwig-Maximilians-Universität, Feodor-Lynen-Strasse 25, 81377 Munich, Germany;2. Gene Center, Ludwig-Maximilians-Universität, Feodor-Lynen-Strasse 25, 81377 Munich, Germany
Abstract:
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  • Keywords:cryoelectron microscopy  DNA double-strand break repair  ataxia-telangiectasia  ATM  protein kinase  cancer  telomere length maintenance  DNA damage response
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