SimArray: a user-friendly and user-configurable microarray design tool |
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Authors: | Richard P Auburn Roslin R Russell Bettina Fischer Lisa A Meadows Santiago Sevillano Matilla Steven Russell |
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Affiliation: | (1) Department of Genetics, University of Cambridge, Cambridge, UK |
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Abstract: |
Background Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Regardless of the intended application, efficient production and appropriate array design are key determinants of experimental success. Inefficient production can make larger-scale studies prohibitively expensive, whereas poor array design makes normalisation and data analysis problematic. |
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