Thyroid And Aging |
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| Institution: | 1. From the Division of Endocrinology Metabolism, Mayo Clinic, Rochester, Minnesota.;1. From the Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;2. Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea;3. Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea;4. Department of Surgery (Busan Cancer Center), Pusan National University Hospital, Pusan National University College of Medicine, Busan, South Korea.;1. HLA and Hospital Universitario de Guadalajara, Guadalajara, Spain;2. Faculty of Medicine, University of Alcalá, Madrid, Spain;3. Centro de Endocrinología, Nutrición y Diabetes, Madrid, Spain;4. Division of Endocrinology, Veterans Administration Medical Center, University of Arizona College of Medicine, Phoenix, AZ, United States;5. Endocrine Surgery, Unidad de Medicina y Cirugía Endocrino-Metabólica, Hospital Nuestra Señora del Rosario, Madrid, Spain;6. Washington DC Veterans Administration Medical Center, Georgetown University School of Medicine, George Washington University School of Medicine, Washington, DC, United States;1. From the Department of Endocrinology, Albany Medical Center, Albany, New York. |
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| Abstract: | Objective: Review physiologic thyroid function changes with aging and emphasize careful interpretation of tests in the aging population.Methods: Literature review.Results: Using age-specific thyroid-stimulating hormone (TSH) reference ranges should minimize or avoid the unnecessary diagnosis of thyroid disease in elderly patients. Subclinical thyroid dysfunction and abnormal TSH with normal thyroid levels may improve with time, so careful monitoring of thyroid function is recommended. Overt thyroid disease should always be treated.Conclusion: Clinical judgement is always warranted to decide how and when to treat subclinical thyroid disease in the elderly.Abbreviations: FT4 = free thyroxine; rT3 = reverse triiodothyronine; T3 = triiodothyronine; T4 = thyroxine; TFT = thyroid function test; TSH = thyroid-stimulating hormone |
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