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Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate |
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| Authors: | Russell L Legg Jessica R Tolman Cameron T Lovinger Edwin D Lephart Kenneth DR Setchell Merrill J Christensen |
| Institution: | (1) Department of Nutrition, Dietetics and Food Science, Brigham Young University, Provo, UT 84602, USA;(2) Department of Physiology, Developmental Biology and Neuroscience, Brigham Young University, Provo, UT 84602, USA;(3) Department of Pediatrics, Children's Hospital Medical Center, Cincinnati, OH 45229, USA;(4) BYU Cancer Research Center, Brigham Young University, Provo, UT 84602, USA |
| Abstract: | BackgroundHigh dietary intake of selenium or soybean isoflavones reduces prostate cancer risk. These components each affect androgen-regulated gene expression. The objective of this work was to determine the combined effects of selenium and isoflavones on androgen-regulated gene expression in rat prostate. |
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