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Slow conduction and gap junction remodeling in murine ventricle after chronic alcohol ingestion
Authors:Yu-Jun Lai  Chung-Lieh Hung  Ray-Ching Hong  Ya-Ming Tseng  Cheng-I Lin  Yu-Shien Ko  Cheng-Ho Tsai  Hung-I Yeh
Affiliation:(1) Departments of Internal Medicine and Medical Research, Mackay Memorial Hospital, Mackay Medicine, Nursing and Management College, Mackay Medical College, New Taipei City, Taiwan;(2) Departments of Physiology and Biophysics, National Defense Medical Center, Taipei, Taiwan;(3) The First Cardiovascular Division, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan
Abstract:

Background  

Long-term heavy alcohol drinkers are prone to the development of cardiac arrhythmia. To understand the mechanisms, we evaluated the cardiac structural and electrophysiological changes in mice chronically drinking excessive alcohol.
Keywords:alcohol   arrhythmia   remodeling   gap junctions   optical mapping
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