The battle over inhibitory synaptic plasticity in satiety brain circuits |
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| Authors: | Younts Thomas J Castillo Pablo E |
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| Affiliation: | 1 Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY 10461, USA |
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| Abstract: | ![]()
The synaptic basis underlying food intake is poorly understood. New research shows that an animal's satiety state dictates the polarity of long-term inhibitory synaptic plasticity in the hypothalamus, which is mediated by an activity-dependent competition between endocannabinoid and nitric oxide signaling. |
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