Vasopressin analog delays extinction of classically conditioned bradycardia |
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Authors: | Linda L Hernández DA Powell |
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Institution: | 1. Neuroscience Laboratory, Wm. Jennings Bryan Dorn Veterans'' Hospital, Columbia, SC 29201 USA;2. Department of Psychology, University of South Carolina, Columbia, SC 29208 USA |
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Abstract: | Albino rabbits were subjected to Pavlovian (classical) conditioning and extinction of concomitant heart rate and eyeblink responses. Sixty minutes before each of three extinction sessions animals were treated with 5 or 20 μg/kg of deamino-dicarba-arginine-8-vasopressin or saline. Vasopressin treatment delayed extinction of bradycardiac conditioned responses but did not affect concomitant eyeblink conditioned responses. It was concluded that classically conditioned autonomic responses may be useful tools for studying the effects of peptides on learning. |
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Keywords: | Vasopressin Peptides Classical (Pavlovian) conditioning Heart rate Eyeblink Learning Rabbits |
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