Accuracy of dose calculation on iterative CBCT for head and neck radiotherapy |
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| Institution: | 1. Department of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan;2. Graduate School of Health Sciences, Kumamoto University, Kumamoto, Japan;3. Department of Medical Radiation Sciences, Faculty of Life Science, Kumamoto University, Kumamoto, Japan;4. Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Osaka, Japan;1. Department of Medical Physics, University Hospital “Maggiore della Carità,” Novara, Italy;2. Medical Physics Department, Veneto Institute of Oncology IOV–IRCCS, Padua, Italy;3. Tecnologie Avanzate, Torino, Italy;4. Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC di Fisica Sanitaria, Dipartimento di diagnostica per immagini, radioterapia oncologica ed ematologia, Rome, Italy;5. U.O.C. Fisica Sanitaria, ASL Teramo, Italy;6. SC Fisica Sanitaria, A.O. Ordine Mauriziano di Torino, Italy;7. Department of Medical Physics, A.O. U. di Modena, Modena, Italy;8. University of Turin, Post Graduate School in Medical Physics, Turin, Italy;9. Medical Physics Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, FC, Italy;10. Medical Physics Department, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, FC, Italy;11. Ospedale regionale \"Umberto Parini\" Azienda USL VDA, Fisica Sanitaria, Italy;12. Medical Physics Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy;13. School of Engineering, Cardiff University, Cardiff, Wales, UK;14. ASLCN2 di Alba e Bra, Italy;15. Department of Medical Physics, St. Orsola-Malpighi Hospital, Bologna, Italy;p. Radiotherapy unit, INI Città bianca Veroli (FR), Italy;q. IEO, European Institute of Oncology IRCCS, Unit of Medical Physics, Milan, Italy;r. U.O.C. di Fisica Medica ULSS 3 Serenissima, Italy;s. University of Turin, Department of Oncology, Turin, Italy;t. School of Bioengineering and Medical-Surgical Sciences, Politecnico di Torino, Turin, Italy;1. Department of Medical Physics, Gdynia Oncology Centre, Powstania Styczniowego 1, 81-519 Gdynia, Poland;2. Department of Electroradiology, Poznan University of Medical Sciences, Garbary 15, 61-866 Poznan, Poland;3. Department of Medical Physics, Greater Poland Cancer Centre, Garbary 15, 61-866 Poznan, Poland;1. Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand;2. Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand |
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| Abstract: | PurposeTo evaluate the feasibility of the use of iterative cone-beam computed tomography (CBCT) for dose calculation in the head and neck region.MethodsThis study includes phantom and clinical studies. All acquired CBCT images were reconstructed with Feldkamp–Davis–Kress algorithm-based CBCT (FDK-CBCT) and iterative CBCT (iCBCT) algorithm. The Hounsfield unit (HU) consistency between the head and body phantoms was determined in both reconstruction techniques. Volumetric modulated arc therapy (VMAT) plans were generated for 16 head and neck patients on a planning CT scan, and the doses were recalculated on FDK-CBCT and iCBCT with Anisotropic Analytical Algorithm (AAA) and Acuros XB (AXB). As a comparison of the accuracy of dose calculations, the absolute dosimetric difference and 1%/1 mm gamma passing rate analysis were analyzed.ResultsThe difference in the mean HU values between the head and body phantoms was larger for FDK-CBCT (max value: 449.1 HU) than iCBCT (260.0 HU). The median dosimetric difference from the planning CT were <1.0% for both FDK-CBCT and iCBCT but smaller differences were found with iCBCT (planning target volume D50%: 0.38% (0.15–0.59%) for FDK-CBCT, 0.28% (0.13–0.49%) for iCBCT, AAA; 0.14% (0.04–0.19%) for FDK-CBCT, 0.07% (0.02–0.20%) for iCBCT). The mean gamma passing rate was significantly better in iCBCT than FDK-CBCT (AAA: 98.7% for FDK-CBCT, 99.4% for iCBCT; AXB: 96.8% for FDK_CBCT, 97.5% for iCBCT).ConclusionThe iCBCT-based dose calculation in VMAT for head and neck cancer was accurate compared to FDK-CBCT. |
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| Keywords: | Iterative CBCT Dose calculation Adaptive radiation therapy Head and neck cancer |
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