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Yorkie-Warts Complexes are an Ensemble of Interconverting Conformers Formed by Multivalent Interactions
Institution:1. Department of Biochemistry & Biophysics, Oregon State University, Corvallis, OR 97331, USA;2. Department of Chemistry & Biochemistry, University of Oregon, Eugene, OR 97403, USA;3. Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA;4. Materials Science Institute, University of Oregon, Eugene, OR 97403, USA;1. Viral Recombination Section, HIV Dynamics and Replication Program, National Cancer Institute, Frederick, MD 21702, USA;2. Viral Mutation Section, HIV Dynamics and Replication Program, National Cancer Institute, Frederick, MD 21702, USA;1. School of Biological Sciences, University of Southampton, Southampton SO17 1BJ, UK;2. Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK;3. Division of Structural Biology, University of Oxford, Wellcome Centre for Human Genetics, Oxford OX3 7BN, UK;1. BioBank, The First Affiliated Hospital of Xi''an Jiaotong University, Shaanxi 710061, China;2. Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, SW7 2AZ London, United Kingdom;3. Instrument Analysis Center of Xi''an Jiaotong University, Xi''an, Shaanxi 710049, China;4. School of Pharmacy, Xi''an Jiaotong University, Xi''an 710061, China;5. National Facility for Protein Science, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, China;1. Goodman Cancer Research Centre, McGill University, 1160 Pine Avenue West, Montreal, Québec H3A 1A3, Canada;2. Departments of Biochemistry, McGill University, 1160 Pine Avenue West, Montreal, Québec H3A 1A3, Canada;3. Medicine, McGill University, 1160 Pine Avenue West, Montreal, Québec H3A 1A3, Canada;4. Oncology, McGill University, 1160 Pine Avenue West, Montreal, Québec H3A 1A3, Canada;5. Department of Biology, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Québec J1K 2R1, Canada;6. Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Québec J1K 2R1, Canada;1. Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA;2. Physics and Materials Science Research Unit, University of Luxembourg, L-1511 Luxembourg, Luxembourg;3. Department of Physics, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA
Abstract:
Keywords:WW domain  PPXY motif  intrinsically disordered protein  Hippo signaling pathway  protein-protein interaction  PPXY"}  {"#name":"keyword"  "$":{"id":"k0035"}  "$$":[{"#name":"text"  "_":"Proline-Proline-any amino acid-Tyrosine  WT"}  {"#name":"keyword"  "$":{"id":"k0045"}  "$$":[{"#name":"text"  "_":"wild type  MS"}  {"#name":"keyword"  "$":{"id":"k0055"}  "$$":[{"#name":"text"  "_":"mass spectrometry  ITC"}  {"#name":"keyword"  "$":{"id":"k0065"}  "$$":[{"#name":"text"  "_":"isothermal titration calorimetry
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