A unified theory for estimation of cardiac output, volumes of distribution and renal clearance from indicator dilution curves.

The assembly of cellular structures is considered to be a linear process that begins with the synthesis of structural molecules. At various points during assembly, additional genetic information may be required for proper assembly. Based on the location of genetic information expression during assembly, structure biogenesis can be grouped into four categories: (1) those which require only information for the synthesis of structural macromolecules; (2) those which require information for the post-translational modification of precursor structural macromolecules; (3) those which require genetic information for the actual assembly step; and (4) those which require information for post-assembly modification of the structure. Examples are given to illustrate and document each of these types of assembly reactions. Further, the usefulness of this scheme for understanding intracellular and extracellular assembly processes is discussed.