Conservation of locus-specific microsatellite variability across species: a comparison of two Drosophila sibling species, D. melanogaster and D. simulans |
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Authors: | Harr B; Zangerl B; Brem G; Schlotterer C |
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Institution: | Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat Wien, Austria. |
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Abstract: | Fifteen microsatellite loci were studied in Drosophila melanogaster and
Drosophila simulans, two closely related sibling species which split 2- 3.5
MYA. Within-species variances in repeat number were found to differ up to
1,000-fold among individual microsatellite loci. A significant correlation
of log variances between both species indicated a locus- specific mutation
rate of microsatellites. Hence, locus-specific effects are apparently among
the major forces influencing microsatellite variation and deserve more
consideration in microsatellite analysis.
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