(1) College of Life and Environmental Sciences, Korea University, 136-713 Sungbuk-gu, Anam-dong 5-1, Seoul, Korea;(2) Jeil Biotechservices Inc., Daecheon-dong 739, 704-330 Dalseo-gu, Daegu, Korea
Abstract:
Serum-free media containing no animal-derived components were assessed for their efficacy to produce live attenuated varicella virus. Serum-free medium containing an ultrafiltrate of soy protein acid hydrolysate and lipid resulted in a viral production yield comparable to media containing fetal bovine serum, indicating that varicella virus can be produced without the risk of contamination associated with the use of bovine serum.
Revisions requested; Revisions requested 20 December 2004; Accepted 21 December 2004