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Translation initiation region sequence preferences in <Emphasis Type="Italic">Escherichia coli</Emphasis>
Authors:Vladimir Vimberg  Age Tats  Maido Remm  Tanel Tenson
Institution:(1) Institute of Technology, University of Tartu, Nooruse 1, Tartu, 50411, Estonia;(2) Department of Bioinformatics, Institute of Molecular and Cell Biology, University of Tartu, Riia 23, Tartu, 51010, Estonia
Abstract:

Background  

The mRNA translation initiation region (TIR) comprises the initiator codon, Shine-Dalgarno (SD) sequence and translational enhancers. Probably the most abundant class of enhancers contains A/U-rich sequences. We have tested the influence of SD sequence length and the presence of enhancers on the efficiency of translation initiation.
Keywords:
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