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Effect of protein-energy deficiency on the composition of the glial population of the mouse neocortex
Authors:D I Medvedev  O B Savrova  T V Iakovleva
Abstract:A quantitative analysis of the cellular elements composition of the neocortex has been performed in 40-day-old mice, that have been given full-bodied synthetic diet (10% of protein) and the diet with the half concentration of the nutritive substances (5% of protein) beginning from the 10th day of their life. The protein-energetic insufficiency during the postnatal period produces retardation in the formation and differentiation processes of oligodendrogliocytes, as well as results in decrease of gliocytesatellites in the neocortex.
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