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Inactivation of Mycobacterium avium subsp. paratuberculosis in Cow's Milk by Means of High Hydrostatic Pressure at Mild Temperatures
Authors:Toms Lpez-Pedemonte  Iker Sevilla  Joseba M Garrido  Gorka Aduriz  Buenaventura Guamis  Ramn A Juste  and Artur X Roig-Sagus
Institution:Tomás López-Pedemonte, Iker Sevilla, Joseba M. Garrido, Gorka Aduriz, Buenaventura Guamis, Ramón A. Juste, and Artur X. Roig-Sagués
Abstract:Two strains of Mycobacterium avium subsp. paratuberculosis (3644/02 and ATCC 19698) were inoculated (approximately 6 log CFU/ml) into sterilized milk to evaluate inactivation by high hydrostatic pressure. Reductions of M. avium subsp. paratuberculosis increased with pressure level. Significant differences were also found between M. avium subsp. paratuberculosis strains and between the media used. Average reductions of 4 log CFU/ml after treatment with 500 MPa are comparable to those caused by thermal treatments.
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