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Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: A case report |
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| Authors: | Dr Kazuo Tamura Masanori Takeuchi Nobuyuki Hirakawa Kiyokazu Toyoda Masaru Minoda |
| Institution: | (1) Department of Internal Medicine, Miyazaki Prefectural Hospital, 5-30 Kitatakamatsu-cho, 880 Miyazaki, Japan;(2) Department of Surgery, Miyazaki Prefectural Hospital, 5-30 Kitatakamatsu-cho, 880 Miyazaki, Japan;(3) Department of Urology, Miyazaki Prefectural Hospital, 5-30 Kitatakamatsu-cho, 880 Miyazaki, Japan |
| Abstract: | The 35-year-old man with myelodysplastic syndrome (MDS) and granulocytopenia with dry cough and high fever was eventually found to have a left perinephric abscess ofStaphylococcus aureus. He underwent left nephrectomy and drainage of perinephric space in conjunction with appropriate antibiotics. However, because of persistent granulocytopenia,Staph. aureus never cleared up with formation of only poor granulation. Recombinant human granulocyte colony-stimulating factor (G-CSF) was added to the above treatment leading to prompt improvement in granulocytopenia and emergence of the good granulation tissue. G-CSF will probably become one of the important agents in treating MDS with granulocytopenia. |
| Keywords: | granulocyte colony-stimulating factor myelodysplastic syndrome perinephric abscess refractory anemia renal abscess |
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