| Abstract: | A total of 13 ecs mutations affecting female fertility were isolated by complementation analysis. Seven of them were rearrangements with the br complementation group phenotype. Six other mutations had no cytologically detectable rearrangements and behaved as completely or partially non-complementing alleles of the ecs locus. All viable combinations of the above 13 mutations disturbed female fertility. Sterile were all fully viable compounds carrying any of these mutations and rearrangements Df (1) sta, T(1; 3)sta, Df(1)St490, previously localized on the molecular map distally to the ecs locus. According to data on location on molecular map of lesions affecting fertility, at least two elements at the ecs locus seem essential for this function: the most distal (left) cis-acting zone with no effect on viability and a sequence within the limits of the essential part of the ecs locus. Disturbance of any of these zones or their separation in the rearranged chromosomes lead to female sterility. |
