Lipid membranes with grafted polymers: physicochemical aspects |
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| Authors: | Marsh Derek Bartucci Rosa Sportelli Luigi |
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| Institution: | Max-Planck-Institut für Biophysikalische Chemie, Abteilung Spektroskopie, Am Fassberg 11, D-37077 G?ttingen, Germany. dmarsh@gwdg.de |
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| Abstract: | Membranes grafted with water-soluble polymers resist protein adsorption and adhesion to cellular surfaces. Liposomes with surface-grafted polymers therefore find applications in drug delivery. The physicochemical properties of polymer-grafted lipid membranes are reviewed with mean-field and scaling theories from polymer physics. Topics covered are: mushroom-brush transitions, membrane expansion and elasticity, bilayer-micelle transitions, membrane-membrane interactions and protein-membrane interactions. |
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