Reagents for the selective immobilization of oligonucleotides on solid supports |
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| Authors: | Kvach Maksim V Prokhorenko Igor A Ustinov Alexey V Gontarev Sergei V Korshun Vladimir A Shmanai Vadim V |
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| Affiliation: | Institute of Physical Organic Chemistry NAS, Minsk, Belarus. |
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| Abstract: | New reagents (CPGs and phosphoramidites) for automatic solid phase synthesis of modified oligonucleotides were designed. Three oligonucleotides carrying fluorescent label at the 5'-terminus and an anchor group at the 3'-terminus were prepared and their immobilization in orthogonal conditions on solid supports was studied. |
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