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Clematichinenoside inhibits VCAM-1 and ICAM-1 expression in TNF-α-treated endothelial cells via NADPH oxidase-dependent IκB kinase/NF-κB pathway
Institution:1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Konkuk University School of Medicine, 120-1, Neungdong-ro, Hwayang-dong, Gwangjin-gu, Seoul 143-729, Korea;2. Department of Molecular Medicine, Ewha Womans University Medical School, 911-1, Mok-6-dong, Yangcheon-gu, Seoul 158-710, Korea;3. Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Ulsan College of Medicine, 388-1 Pungnap2-dong, Songpa-gu, Seoul 138-736, Korea;4. Institute of Pharmaceutical Research and Development, College of Pharmacy, Wonkwang University, and Hanbang Body-Fluid Research Center, Wonkwang University, Iksan 570-749, Korea;5. Department of Pharmacology, School of Medicine, Eulji University, 77 Gyeryong-ro 771 Beon-gil, Jung-gu, Daejeon 301-746, Korea
Abstract:
Keywords:Clematichinenoside  Adhesion  NF-κB  Reactive oxygen species  NADPH oxidase
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