Ionization state of myo-inositol 1,4,5-trisphosphate: correlation with binding properties. |
| |
| Authors: | L Schmitt G Schlewer B Spiess |
| |
| Institution: | Centre de Neurochimie du CNRS, Départment de Pharmacochimie Moléculaire, Strasbourg, France. |
| |
| Abstract: | The comparison between the ionization state and the binding properties on brain membrane receptors of the synthetized myo-inositol 1,4,5-trisphosphate lead to the conclusion that the biological active species may be either the monoprotonated or the fully deprotonated trisphosphate. |
| |
| Keywords: | |
|
|
