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Synthesis and antianemic activity of nanosized biocomposite ferroarabinogalactan
Authors:G. P. Aleksandrova  I. M. Krasnikova  L. A. Grishchenko  S. A. Medvedeva  T. D. Chetverikova
Affiliation:1.Favorskii Institute of Chemistry, Siberian Branch,Russian Academy of Sciences,Irkutsk,Russia;2.Irkutsk State Medical University,Irkutsk,Russia
Abstract:An aggregation-stable highly resistant nanobiocomposite, a stimulator of hemopoiesis, has been synthesized and characterized by physicochemical methods. The biocomposite represents nanodisperse iron oxides encapsulated into a biocompatible biogenic matrix of arabinogalactan from Siberian larch (Larix sibirica). The effect of the novel iron-containing nanobiocomposite on the erythrocytic system in experimental anemia has been studied. It has been shown that ferroarabinogalactan produces an iron-stabilizing effect; its use qualitatively corrects iron deficiency and reduces manifestations of anemia.
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