Sequence-specific 1H, 15N and 13C resonance assignments of Art v 1: a proline-rich allergen of Artemisia vulgaris pollen |
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| Authors: | Guilherme Razzera Gabriele Gadermaier Marcius S Almeida Fatima Ferreira Fabio C L Almeida Ana Paula Valente |
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| Institution: | (1) Centro Nacional de Ressonancia Magnética Nuclear, Universidade Federal do Rio de Janeiro, Instituto de Bioquímica Médica, Rio de Janeiro, Brazil;(2) Christian Doppler Laboratory for Allergy Diagnosis and Therapy, University of Salzburg, Salzburg, Austria |
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| Abstract: | Art v 1 is the major allergen of Artemisia vulgaris. The IgE raised against Art v 1 not only can cross-react with other proteins from the Asteraceae family members but also with components of various forms of food. Art v 1 is an important target for immunotherapy strategies,
including vaccination with hypoallergenic derivatives or chimeras. We report the 1H, 13C, and 15N resonance assignments of the recombinant Art v 1 and identification of secondary structures based on 13C chemical shifts. |
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| Keywords: | Art v 1 NMR assignments Proline-rich allergen Defensin-like |
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