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Linkage analysis of seven kindreds with the X-linked lymphoproliferative syndrome (XLP) confirms that the XLP locus is near DXS42 and DXS37
Authors:James C Skare  Helen L Grierson  John L Sullivan  Robert L Nussbaum  David T Purtilo  Bakary S Sylla  Gilbert M Lenon  Dorothy S Reilly  Bradley N White  Aubrey Milunsky
Institution:(1) Center for Human Genetics and Departments of Pediatrics and Microbiology, Boston University School of Medicine, 02118 Boston, MA, USA;(2) Department of Pathology and Microbiology, University of Nebraska Medical Center, 68105 Omaha, NE, USA;(3) Department of Pediatrics, Molecular Genetics, and Microbiology, University of Massachusetts Medical School, 01655 Worcester, MA, USA;(4) Howard Hughes Medical Institute and Department of Human Genetics, University of Pennsylvania School of Medicine, 19104 Philadelphia, PA, USA;(5) International Agency for Research on Cancer, Lyon, France;(6) Department of Biology, Queens University, Kingston, Ontario, Canada;(7) L402, Boston University School of Medicine, 80 East Concord Street, 02118 Boston, MA, USA
Abstract:Summary Analysis of seven kindreds indicates that the XLP locus exhibits 1% recombination with DXS42 (lod = 17.5) and no recombination with DXS37 (lod = 13.3).
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