Cyclic azaphilones daldinins E and F from the ascomycete fungus Hypoxylon fuscum (Xylariaceae) |
| |
Authors: | Quang Dang Ngoc Hashimoto Toshihiro Tanaka Masami Stadler Marc Asakawa Yoshinori |
| |
Institution: | Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan. |
| |
Abstract: | Phytochemical examination of the methanolic extract of fruit bodies of the Xylariaceous ascomycete fungus Hypoxylon fuscum led to the isolation of two azaphilone derivatives named daldinins E and F together with two known compounds daldinin C and 4,5,4',5'-tetrahydroxy-1:1'-binaphthyl using a combination of reversed phase HPLC and high performance gel permeation chromatography. Their structures were determined by 2D NMR, MS, IR, UV, and CD spectroscopy. Their antioxidative activities were also estimated by an indication of a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging effect. The chemosystematics of Hypoxylon is discussed. |
| |
Keywords: | Daldinin Hypoxylon Xylariaceae Fungus Azaphilone Chemosystematics |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|