| 枯草芽孢杆菌蛋白质分泌机制研究进展 |
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| 引用本文： | 周冰,张惟材. 枯草芽孢杆菌蛋白质分泌机制研究进展[J]. 生物技术通讯, 2004, 15(3): 281-284 |
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| 作者姓名： | 周冰 张惟材 |
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| 作者单位： | 军事医学科学院,生物工程研究所,北京,100071 |
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| 摘 要： | 综述了枯草芽孢杆菌不同蛋白质分泌机制，重点讨论了大多数细菌蛋白分泌的Sec途径，包括Sec途径的信号肽，信号肽酶，SecYEG通道，与分泌有关的各种细胞因子以及Sec途径的限制因素，此外还简要讨论了Tat途径，该途径能够转运折叠迅速或归密的蛋白质。
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| 关 键 词： | 枯草芽孢杆菌 蛋白质 分泌机制 细胞因子 |
| 文章编号： | 1009-0002(2004)03-0281-04 |
| 修稿时间： | 2004-02-03 |
Advances in protein secretion mechanism of Bacillus subtilis |
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| ZHOU Bing,ZHANG Wei-cai Institute of Biotechnology,Academy Military Medical Sciences,Beijing,China. Advances in protein secretion mechanism of Bacillus subtilis[J]. Letters in Biotechnology, 2004, 15(3): 281-284 |
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| Authors: | ZHOU Bing ZHANG Wei-cai Institute of Biotechnology Academy Military Medical Sciences Beijing China |
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| Affiliation: | ZHOU Bing,ZHANG Wei-cai Institute of Biotechnology,Academy Military Medical Sciences,Beijing100071,China |
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| Abstract: | The protein secretion mechanisms in Bacillus subtilis are reviewed.The Sec pathway,including signal peptide,signal peptidase,SecYEG channel,cytosolic factors and its bottlenecks,are chiefly discussed.In addition,the Tat path-wayis briefly reviewed,which is corresponding to the passage of rapid and tight folded proteins. |
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| Keywords: | protein secretion mechanism Bacillus subtilis |
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