Microfluorometric study of pH in frog nerves at rest and during rhythmic stimulation]

With the use of microspectrofluorimetry the pH-dynamics in the frog nerve at rest and during rhythmic excitation was investigated. Rhythmic excitation results in an increase of hydrogen ion concentration in the nerve fibres. Metabolic and ion channel inhibitors affect intracellular pH changes. The results obtained suggest different role of various transport systems (sodium pump and ion channels) in the regulation of pH at rest and during rhythmic excitation.