Robust regression-based analysis of drug-nucleic acid binding |
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Authors: | Booth David E Lee Kidong |
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Institution: | Graduate School of Management, Kent State University, Kent, OH 44242, USA. dbooth@kent.edu |
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Abstract: | Outlier detection can be very important in analyzing data from Scatchard plots. In this study, a robust (outlier-resistant) regression procedure was used in conjunction with a Scatchard plot to study the binding of the methylphenazinium cation with double-stranded DNA. The procedures, their results, and their advantages are discussed. |
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