3H]-Nitrendipine binding in developing dissociated fetal mouse spinal cord neurons |
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| Authors: | M J Litzinger D E Brenneman |
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| Affiliation: | Laboratory of Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md. 20205, USA |
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| Abstract: | The development of [3H]-nitrendipine binding was investigated in spinal cord neurons. Kinetic studies indicated two classes of binding sites which were present throughout development and the dissociation constants (Kd) and Bmax increased during development. [3H]-nitrendipine binding during development was characterized by a plateau on days 3-5 with maximal binding observed on day 19 after plating. |
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