阻塞型睡眠呼吸暂停低通气综合征与代谢综合征组分关系探讨

目的：探讨阻塞型睡眠呼吸暂停低通气综合征（OSAHS）与代谢综合征（MS）组分关系。方法：对我院2003年1月至2010年7月39例诊断为0SAHS住院患者进行回顾性调查，30例同期住院病人为对照组，均记录年龄、性别，测量身高、体重、血压，检测空腹血糖、血脂，分析OSAHS患者合并MS组分情况。结果：1．OSAHS组与对照组比较，体重指数（BMI）、血压、血清甘油三酯、总胆固醇、低密度脂蛋白胆固醇、载脂蛋白Al升高，高密度脂蛋白胆固醇降低（P〈0．05）；2．OSAHS组与对照组相比较，无MS组分比例低于对照组，差异有统计学意义（P〈0．05）；3．OSAHS组与对照组相比较，OSAHS组合并MS组分，包括BMI〉25Kg／m2，血脂紊乱的比例，均高于对照组，差异有统计学意义（P〈0．05）。结论：OSAHS患者易合并代谢综合征组分。

The Relationship between Obstructive Sleep Apnea Hypoventilation Syndrome and Components of Metabolic Syndrome

Objective： To explore the relationship between obstructive sleep apnea hypopnea syndrome （OSAHS） and components of metabolic syndrome （MS）. Methods： 39 cases of hospitalized patients diagnosed with OSAHS were studied retrospectively from January 2003 to July 2010. 30 cases of hospitalized patients at the same time with no OSAHS were collected as control group. Age, sex, body height, body weight, blood pressure, fasting blood glucose, lipid profile were recorded. Results： 1. The body mass index （BMI）, blood pressure, serum triglyceride, total cholesterol, low-density lipoprotein cholesterol, apolipoprotein A1 were higher and low-density lipoprotein cholesterol were lower in patients with OSAHS than in controls （P〈0.05）. 2. The prevalence of those without any components of MS in OSAHS was lower than controls （P〈0.05）. 3, The prevalence of those with combined components of MS, including BMI ≥ 25kg/m2 and lipid disorders was higher in OSAHS group than in control group. （P〈0.05）, Conclusions： Patients wtith OSAHS were proned to develope components of MS.