预防心脏手术中体外循环致肺损伤的研究进展

体外循环是心内直视手术的一种重要手段，随着体外循环装置、心肌保护措施和心脏外科技术的不断完善与提高，心内直视手术并发症的发生率和死亡率已大大下降。但肺损伤仍是CPB后的主要并发症之一，而肺损伤后气体交换障碍可能造成严重的并发症，甚至死亡。本文综述了体外循环心脏手术后肺损伤的发生机制及预防措施的研究进展。

Prevention of Lung Injury Caused by Cardiopulmonary Bypass during Cardiac Surgery

Cardiopulmonary bypass （CPB） plays an important role in cardiac surgery. With the improvements of CPB devices, myocardial protection techniques and surgery skills, mortality and morbidity of cardiac surgery decreased significantly. However, pulmonary dysfunction remains one of the major CPB complications. Abnormal gas exchange due to pulmonary dysfunction may result in many other complications, even death. This article reviews the progress of mechanics and preventive strategies of pulmonary dysfunction.