Optimization of dose and image quality of paediatric cardiac catheterization procedure |
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Affiliation: | 1. Department of Physics, Faculty of Mathematics and Natural Sciences, University of Indonesia, 16424, Depok, Indonesia;2. Department of Biomedical Imaging, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia;3. Department of Imaging & Pathology, Catholic University of Leuven, 3000, Leuven, Belgium;1. Department of Traumatic Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China;2. Department of Preventive Medicine, The Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China;3. Department of Biomedical Engineering, Wayne State University, Detroit, Michigan;1. Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran;2. Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran;1. Division of Pediatric Urology, James Buchanan Brady Urological Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland;2. The Division of Pediatric Radiology, Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, Maryland;1. Centre d''Assurance de Qualité des Applications Technologiques dans le domaine de la Santé, Bourg-la-Reine, France;2. Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Interventional Cardiology Department, Générale de Santé, France;3. Institut Cardiovasculaire Paris Sud, Hôpital Privé Claude Galien, Interventional Cardiology Department, Générale de Santé, France;1. National Atomic Energy Commission, Av. Libertador 8250, C1429BNP C. A. B. A Buenos Aires, Argentina;2. Sanatorium Dr Julio Méndez, Av. Avellaneda 551, C1405CNF C. A. B. A Buenos Aires, Argentina |
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Abstract: | The purpose of this study is to quantify the quality of the available imaging modes for various iodine-based contrast agent concentration in paediatric cardiology. The figure of merit (FOM) was defined as the squared signal to noise ratio divided by a patient dose related parameter. An in house constructed phantom simulated a series of vessel segments with iodine concentrations from 10% or 30 mg/cc to 16% or 48 mg/cc of iodine in a blood plasma solution, all within the dimensional constraints of a paediatric patient. The phantom also used test inserts of tin (Sn). Measurements of Entrance Surface Air Kerma (ESAK) and exit dose rate were performed along with calculations of the signal-to-noise ratio (SNR) of all the objects. A first result showed that it was favourable to employ low dose fluoroscopy mode and lower frame rate modes in cine acquisition if dynamic information is not critical. Normal fluoroscopy dose mode provided a considerably higher dose level (in comparison to low dose mode) with only a slight improvement in SNR. Higher frame rate cine modes should be used however when the clinical situation dictates so. This work also found that tin should not be intended as iodine replacement material for research purposes due to the mismatching SNR, particularly on small vessel sizes. |
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Keywords: | Cardiac catheterization Dose Figure of merit Image quality Optimization Paediatric |
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