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Simultaneous achievement of accurate CT number and image quality improvement for myocardial perfusion CT at 320-MDCT volume scanning
Institution:1. Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan;2. The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, USA;3. Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan;4. Department of Radiology, Kumamoto University Hospital, Kumamoto, Japan;1. Heart & Vascular Institute, Cleveland Clinic, Cleveland, OH, USA;2. Cardiovascular Imaging, Imaging Institute, Cleveland Clinic, Desk J1-4, 9500 Euclid Avenue, Cleveland, OH, USA;3. Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA;1. Radiation Oncology Department, Cancer Institute Hospital, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8550, Japan;2. Graduate Division of Health Sciences, Komazawa University, 1-23-1, Komazawa, Setagaya-ku, Tokyo 154-8525, Japan;3. Particle Therapy Division, Research Center for Innovative Oncology, National Cancer Center, 6-5-1, Kashiwanoha, Kashiwashi, Chiba 277-8577, Japan;1. Optoelectronics Group – Department of Engineering, University of Sannio, I-82100 Benevento, Italy;2. University of Napoli Federico II, Department of Physics, I-80126 Napoli, Italy;3. Istituto Nazionale di Fisica Nucleare (INFN) – Sezione di Napoli, I-80126 Napoli, Italy;4. University of Napoli Federico II, Department of Electronical Engineering, I-80125 Napoli, Italy;1. Department of Medicine and Cardiac Imaging, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Taper Building No. 1258, Los Angeles, CA 90048;2. Ohio State University Medical Center, Columbus, Ohio;1. Department of Radiology, Erasmus University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands;2. Department of Cardiovascular Magnetic Resonance, Institut Cardiovasculaire Paris Sud, Hospital Jacques Cartier, Generale de Santé, Massy, France;3. 3rd Division of Cardiology, Medical University of Silesia, Katowice, Poland;4. Department of Cardiology, University Hospital Ramon y Cajal, Madrid, Spain;1. Department of Internal Medicine 2 (Cardiology), University of Erlangen, Ulmenweg 18, D-91054 Erlangen, Germany;2. Radiological Institute, University of Erlangen, Maximiliansplatz 1, D-91054 Erlangen, Germany
Abstract:PurposeTo investigate differences in image-to-image variations between full- and half-scan reconstruction on myocardial CT perfusion (CTP) study.MethodsUsing a cardiac phantom we performed ECG-gated myocardial CTP on a second-generation 320-multidetector CT volume scanner. The heart rate was set at 60 bpm; once per second for a total of 24 s were performed. CT images were acquired at 80- and 120 kVp and subjected to full- and half-scan reconstruction. On images acquired at the same slice level we then measured image-to-image variations, coefficients of variance (CV), and image noise.ResultsThe image-to-image variations with full- and half-scan reconstruction were 1.3 HU vs. 27.2 HU at 80 kVp (p < 0.001) and 0.70 HU vs. 9.3 HU at 120 kVp (p < 0.001) even though the mean HU value was almost the same for both reconstruction methods. The CV of 80- and 120-kVp images of the left ventricular cavity decreased by 0.16% and 0.17%, respectively, with full-scan reconstruction; with half-scan reconstruction it decreased by 3.34% and 2.30%, respectively. Compared with half-scan reconstruction, the image noise was reduced by 27.2% at 80 kVp and by 28.0% at 120 kVp with full-scan reconstruction.ConclusionMyocardial CTP with full-scan reconstruction substantially decreased image-to-image variations and provided accurate CT attenuation.
Keywords:Full-scan reconstruction  Myocardial CT perfusion  Image-to-image variation  Half-scan reconstruction  320-Detector volume scanner
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