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Checkpoint blockade for cancer therapy: revitalizing a suppressed immune system
Affiliation:1. Radiotherapy and OncoImmunology Laboratory, Department of Radiation Oncology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Geert Grooteplein Zuid 32, 6525 GA, Nijmegen, The Netherlands;1. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, United States;2. The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, United States;3. Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, United States;4. The Skip Viragh Center for Pancreatic Cancer Research and Clinical Care, Johns Hopkins University School of Medicine, Baltimore, MD, United States
Abstract:
Keywords:cancer immunotherapy  PD-1  CTLA-4  checkpoint blockade  MDSCs
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