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Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation
Institution:1. Laboratory of Molecular Oncology, Institut de Recherches Cliniques de Montréal (IRCM), Montréal, QC H2W1R7, Canada;2. Department of Immunology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China;3. Department of Rheumatology and Immunology, Tongji Hospital, Huazhong University of Science and Technology (HUST), Wuhan, China;4. Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST), Wuhan, China;5. Center for Autoimmune Genomics and Etiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA;6. Pathobiology and Molecular Medicine Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, USA;7. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA;8. Department of Pathology and Cellular Biology, University of Montreal, Montreal, QC, Canada;9. Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B4, Canada;10. Maisonneuve-Rosemont Hospital Research Center, Montréal, QC, Canada;11. Department of Medicine, University of Montréal, Montréal, QC H3C3J7, Canada;12. Department of Microbiology, Infectious Diseases and Immunology, University of Montréal, Montréal, QC H3C3J7, Canada;13. Department of Medicine, McGill University, Montréal, QC H3G 1Y6, Canada
Abstract:
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  • Keywords:TMEM16F  ANO6  scramblase  lipid scrambling  plasma membrane repair  pore forming  Listeria  listeriolysin O  phosphatidylserine exposure  extracellular vesicles  calcium
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