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Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway
Affiliation:1. Program in Cancer Biology, Stanford University, Stanford, CA 94305-5120, USA;2. Department of Genetics, Stanford University, Stanford, CA 94305-5120, USA;3. Department of Biology, Stanford University, 327 Campus Drive, Stanford, CA 94305, USA;4. Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA 94305-5120, USA;5. Department of Biology, Faculty of Sciences, Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan;6. Division of Organelle Homeostasis, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
Abstract:
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  • Keywords:CRISPR  genome-wide screen  shRNA  pentose phosphate pathway  peroxisomal import pathway  catalase  phosphogluconate dehydrogenase  oxidative stress  reactive oxygen species
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