Infrared micro-spectroscopic studies of epithelial cells |
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Authors: | Romeo Melissa Mohlenhoff Brian Jennings Michael Diem Max |
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Institution: | Department of Chemistry and Biochemistry, City University of New York, Hunter College, New York, NY 10021, USA. m.romeo@neu.edu |
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Abstract: | We report results from a study of human and canine mucosal cells, investigated by infrared micro-spectroscopy, and analyzed by methods of multivariate statistics. We demonstrate that the infrared spectra of individual cells are sensitive to the stage of maturation, and that a distinction between healthy and diseased cells will be possible. Since this report is written for an audience not familiar with infrared micro-spectroscopy, a short introduction into this field is presented along with a summary of principal component analysis. |
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