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Increased Oxidative Damage and Reduced DNA Repair Enzyme XPD Involvement in High Glucose-Mediated Enhancement of Levobupivacaine-Induced Neurotoxicity
Authors:Liu  ZhongJie  Zhao  Wei  Zhang  QingGuo  Lai  LuYing  Jiang  Shan  Zhang  Jing  Xu  ShiYuan
Affiliation:1.Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, 253 Industrial Road, Guangzhou, 510282, Guangdong Province, China
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Abstract:Neurochemical Research - Levobupivacaine is one of the major clinical local anesthetics, but it can cause neuron toxic damage. Hyperglycemia can cause neuronal DNA oxidative damage and inhibit...
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