Increased Oxidative Damage and Reduced DNA Repair Enzyme XPD Involvement in High Glucose-Mediated Enhancement of Levobupivacaine-Induced Neurotoxicity |
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Authors: | Liu ZhongJie Zhao Wei Zhang QingGuo Lai LuYing Jiang Shan Zhang Jing Xu ShiYuan |
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Affiliation: | 1.Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, 253 Industrial Road, Guangzhou, 510282, Guangdong Province, China ; |
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Abstract: | Neurochemical Research - Levobupivacaine is one of the major clinical local anesthetics, but it can cause neuron toxic damage. Hyperglycemia can cause neuronal DNA oxidative damage and inhibit... |
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