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Early changes in bone mineral density measured by digital X-ray radiogrammetry predict up to 20 years radiological outcome in rheumatoid arthritis |
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| Authors: | Meliha C Kapetanovic Elisabet Lindqvist Jakob Algulin Kjell Jonsson Tore Saxne Kerstin Eberhardt Pierre Geborek |
| Institution: | 1.Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Kioskgatan 3, Lund SE-221 85, Sweden;2.Sectra AB, Teknikringen 20, Linköping, SE-583 30, Sweden;3.Department of Clinical Sciences, Lund, Center for Imaging and Physiology, Lund University, Getingevägen 4, Lund, SE-221 85, Sweden |
| Abstract: | IntroductionChanges in bone mineral density (BMD) in the hand as evaluated by digital X-ray radiogrammetry (DXR) of the second to fourth metacarpal bones has been suggested to predict future joint damage in patients with rheumatoid arthritis (RA). This study's objective was to investigate whether DXR-BMD loss early in the course of the disease predicts the development of joint damage in RA patients followed for up to 20 years. |
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