| NO在脊髓痛觉传递过程中的作用 |
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| 引用本文： | 陈扬林,陈小卫,张文华. NO在脊髓痛觉传递过程中的作用[J]. 生命的化学, 2011, 0(2) |
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| 作者姓名： | 陈扬林 陈小卫 张文华 |
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| 作者单位： | 福建医科大学医学技术与工程学院;福建师范大学生命科学学院; |
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| 摘 要： | 一氧化氮(nitric oxide,NO)是神经元细胞内一种新型的神经递质,它参与多种生命活动,包括脊髓水平的伤害性信息传递过程。研究NO在伤害性信息传递过程中的作用及其机制,有利于阐明痛觉生理和发现疼痛治疗的新手段。本文将NO在慢性痛脊髓伤害性信息传递中的作用及其机制的相关研究进展作一综述。
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| 关 键 词： | 一氧化氮 一氧化氮合成酶 疼痛 |
Role of nitric oxide in spinal nociception transmission |
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| CHEN Yanglin,CHEN Xiaowei,ZHANG Wenhua College of Medical Engineering Technology,Fujian Medical University,Fuzhou ,China,College of Life Sciences,Fujian Normal University,Fuzhou. Role of nitric oxide in spinal nociception transmission[J]. Chemistry of Life, 2011, 0(2) |
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| Authors: | CHEN Yanglin CHEN Xiaowei ZHANG Wenhua College of Medical Engineering Technology Fujian Medical University Fuzhou China College of Life Sciences Fujian Normal University Fuzhou |
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| Affiliation: | CHEN Yanglin1,CHEN Xiaowei1,ZHANG Wenhua2 1College of Medical Engineering Technology,Fujian Medical University,Fuzhou 350004,China,2College of Life Sciences,Fujian Normal University,Fuzhou 350108 |
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| Abstract: | Nitric oxide(NO) acts as a new neurotransmitter in neuron cells.A large body of evidence indicates that NO essentially contributes to the processing of nociceptive signals in the spinal cord.Studying the effect and mechanism of NO underlying pain sensitization is a crucial prerequisite for the development of novel analgesics.This review summarizes the recent advances of NO-dependent signaling pathways in the spinal cord of chronic pain. |
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| Keywords: | nitric oxide nitric oxide synthase pain |
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