Detection of HPV Types and Neutralizing Antibodies in Women with Genital Warts in Tianjin City,China |
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| Authors: | Xue-ling WU Chun-tao ZHANG Xiao-ke ZHU You-chun WANG Beijing China |
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| Institution: | Xue-ling WU 1,Chun-tao ZHANG 1,Xiao-ke ZHU 2 , You-chun WANG 1** (1.Department of Cell Biology,National Institute for the Control of Pharmaceutical , Biological Products (NICPBP),Beijing 100050,China,2.Department of Sexually Transmitted Disease,Tianjin Center for Disease Control,Tianjin 30001l,China) |
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| Abstract: | The serum samples and corresponding cervical swabs were collected from 50 women with genital warts from Tianjin city,China.The neutralizing antibodies against HPV-16,-18,-58,-45,-6 and-11 in serum samples were tested by using pseudovirus-based neutralization assays and HPV DNAs in cervical swabs were also tested by using a typing kit that can detect 21 types of HPV.The results revealed that 36%(18/50)of sera were positive for type-specific neutralizing antibodies with a titer range of 160-2560,of which 22%(... |
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| Keywords: | HPV type Genital warts Pseudovirus Neutralizing antibody DNA |
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