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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

Authors:	Giulia Schiroli Anastasia Conti Samuele Ferrari Lucrezia della Volpe Aurelien Jacob Luisa Albano Stefano Beretta Andrea Calabria Valentina Vavassori Patrizia Gasparini Eralda Salataj Delphine Ndiaye-Lobry Chiara Brombin Julie Chaumeil Eugenio Montini Ivan Merelli Pietro Genovese Luigi Naldini Raffaella Di Micco

Institution:	1. San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy;2. Vita-Salute San Raffaele University, 20132 Milan, Italy;3. Milano-Bicocca University, 20126 Milan, Italy;4. Institute for Biomedical Technologies, National Research Council, 20090 Segrate, Italy;5. Tumor Genomics Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy;6. Inserm U1016, Institut Cochin, 75014 Paris, France;7. CNRS UMR8104, Paris, France;8. Université Paris Descartes, Sorbonne Paris Cité, France;9. CUSSB-University Center for Statistics in the Biomedical Sciences, Vita-Salute San Raffaele University, 20132 Milan, Italy

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Keywords:	genome editing programmable nucleases hematopoietic stem and progenitor cells DNA double strand breaks DNA damage response adeno-associated vector p53 pathway
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