Degradation of 4-hydroxyphenylacetate by Xanthobacter 124X |
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| Authors: | W J J Van Den Tweel R J J Janssens J A M De Bont |
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| Institution: | (1) Department of Microbiology, Agricultural University, H. van Suchtelenweg 4, 6703 CT Wageningen, The Netherlands |
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| Abstract: | Xanthobacter 124X when grom on 4-hydroxyphenylacetate was able to hydroxylate this compound yielding homogenisate. Ring fission of this latter compound gave maleylacetoacetate which was isomerized to fumarylacetoacetate. The isomerase involved resembled maleylacetoacetate isomerases in Gram-negative bacteria in that glutathione was required for activity. Fumarate and acetoacetate were both detected as products of the hydrolysis of fumarylacetoacetate. |
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| Keywords: | 4-hydroxyphenylacetate (4-HPA) metabolism Xanthobacter |
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